This list of 12 letter words containing S and ending in ISM is great for building up your vocabulary. It’s also fantastic for landing those big scoring plays in your favorite word games. Enjoy playing Words With Friends®? Unload a massive double or triple word score against your opponent when you unleash just the right word in just the right place. Pave the path to victory with our advanced search features. And be sure to check the right dictionary in the search options so you’ll only get valid words in your chosen game!